The A169 is shut close to the Gap of Horcum, north of Pickering, after the crash this afternoon (Sunday, August 25).
Emergency providers are on the scene with police urging drivers to keep away from the world.
An air ambulance was additionally known as to the incident.
“The highway could also be closed for a while, so we’re urging drivers to seek out different routes whereas we cope with the incident,” a North Yorkshire Police spokesperson stated.
“Many thanks to your co-operation.”
Extra to observe.